įrom the very beginning, syphilis has been a stigmatized, disgraceful disease each country whose population was affected by the infection blamed the neighboring (and sometimes enemy) countries for the outbreak. Of the aforementioned bacteria, syphilis is the sole sexually transmitted treponemal disease, as the other conditions are transmitted via direct contact with an infected individual. The four members of the bacterial family cannot be differentiated with morphological, chemical or immunological methods. Syphilis is a sexually transmitted disease caused by Treponema Pallidum, a bacterium classified under Spirochaets phylum, Spirochaetales order, Spirochaetaceae family, but there are at least three more known species causing human treponemal diseases such as Treponema pertenue that causes yaws, Treponema carateum causing pinta and Treponema pallidum endemicum-responsible for bejel or endemic syphilis.
